Our paper on two common cancers in golden retrievers is published in PLoS Genetics! Canine B-cell lymphoma and hemangiosarcoma are malignancies of the hematologic system that are clinically and histologically similar to human B-cell non-Hodgkin lymphoma and angiosarcoma. We were part of a large group of scientists, led by Noriko Tonomura and Kerstin Lindblad-Toh, that idenitifed genetic variants associated with a risk of developing these diseases in golden retrievers, and showed they appear to affect pathways involved in T-cell mediated immune response in the tumor. Thank you to all the golden retrievers (and their owners) who made this work possible!
Congratulations to Crystal Harris and our collaborators at MGH and iccdr,b on the publication of their paper “Comparative Proteomic Analysis Reveals Activation of Mucosal Innate Immune Signaling Pathways during Cholera” in Infection and Immunity this week.